Tzeadim › Pregnancy · Second trimester

Comfort & symptoms · Practice

Itchy palms and soles → ask for a bile-acid test

What it is

Mild skin itch is normal. Intense itching of palms/soles, worse at night, without a rash, can be cholestasis of pregnancy — a blood test, then closer monitoring.

every week · from week 24 · until week 42

Sources

• Guidelines for Perinatal Care, 8th edition — ACOG / AAP · checked 02-09-2026

Last reviewed 01-09-2026 · Confidence: high

Compiled with AI assistance from the public sources listed above. Not yet reviewed by a clinician — check anything important against the source, with Tipat Halav or with your doctor.